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Bio-eye Presentation Slide Set

Page 4 of 11


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31. An artist's illustration of the hydroxyapatite material prior to ingrowth of vascular tissue.


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32. Artist's illustration of the hydroxyapatite material after ingrowth of vascular tissue. When placed next to bone, new bone ingrowth occurs; when placed in soft tissue, such as in the orbit, new fibrovascular tissue ingrowth occurs.


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33. Illustration of the Bio-eye Hydroxyapatite Orbital Iimplant in an enucleated socket with the muscles attached. These muscles are attached in the same manner as with some silicone or methylmethacrylate (PMMA) implants.


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34. Illustration of the Bio-eye Hydroxyapatite Orbital Implant showing a peg hole drilled into the implant. Note conjunctival epithelium that lines the hole. Also note the blood vessels growing into the hydroxyapatite implant.


(Click image to enlarge Hydroxyapatite Orbital Implant that has a peg hole to accept the motility/support peg. In this older configuration, the peg is attached directly to the artificial eye. This direct attachment made it difficult for patients to insert the eye. Recent technique favors a ball-and-socket coupling.


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36. Bio-eye Hydroxyapatite Implant using a peg attachment with a ball on its anterior aspect. This ball fits into an indentation on the back of the artificial eye creating a ball-and-socket coupling between the implant and the artificial eye. This variation allows the patient to easily insert the eye.


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37. Histologic section of a rabbit implant. The clear area is hydroxyapatite prior to decalcification. The pink area is fibrovascular tissue that has grown into the pores of the hydroxyapatite. Blood vessels filled with red blood cells are visible. There is essentially no inflammatory reaction and no foreign body giant cells.


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38. A histologic specimen slice taken through the peg hole of the Bio-eye Hdroxyapatite Orbital Implant. The pink area outlining the porous hydroxyapatite is fibrovascular tissue ingrowth. The clear area is hydroxyapatite .


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39. Rabbit showing an orbital implant with a prepared. Note the peg attached to the posterior of the conformer.


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40. Hydroxyapatite Orbital Implant harvested from a rabbit prior to histologic sectioning.


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